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Triciribine phosphate
CAS No. 61966-08-3
Triciribine phosphate( —— )
Catalog No. M33627 CAS No. 61966-08-3
Triciribine phosphate (VD 002) is a highly selective AKT inhibitor that induces cell cycle arrest and cysteinyl asparagin-dependent apoptosis, inhibits neovascularization, and can be used in the study of leukemia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 301 | Get Quote |
|
| 5MG | 490 | Get Quote |
|
| 10MG | 787 | Get Quote |
|
| 25MG | 1132 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameTriciribine phosphate
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NoteResearch use only, not for human use.
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Brief DescriptionTriciribine phosphate (VD 002) is a highly selective AKT inhibitor that induces cell cycle arrest and cysteinyl asparagin-dependent apoptosis, inhibits neovascularization, and can be used in the study of leukemia.
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DescriptionTriciribine phosphate (TCN-P) inhibits amidophosphoribosyltransferase by an allosteric mechanism which affects the first committed step of de novo purine biosynthesis. Triciribine phosphate also inhibits? IMP dehydrogenase which is the first committed step of guanosine nucleotide synthesis. Tricilibine phosphate does not affect ligase activity.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetAkt
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RecptorAkt | Apoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number61966-08-3
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Formula Weight400.28
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Molecular FormulaC13H17N6O7P
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Purity>98% (HPLC)
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Solubility——
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SMILESNC=1C=2C=3C(N(C2)[C@@H]4O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]4O)=NC=NC3N(C)N1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. E C Moore, Inhibition of two enzymes in de novo purine nucleotide synthesis by triciribine phosphate (TCN-P). Biochem Pharmacol. 1989, 38, 22.?
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